Structure
Naphthoquine phosphate, Inhibitor
Naphthoquine phosphate
Purity
98.00%
Synonyms
Naphthoquine phosphate; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
H2O: 3.33mg/mL (5.50mM) Need ultrasonic
DMSO: <1mg/mL (insoluble or slightly soluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
DMSO: <1mg/mL (insoluble or slightly soluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C24H34ClN3O9P2
SMILES
ClC1=CC=C(C(NC2=C(CCCC3)C3=C(O)C(CNC(C)(C)C)=C2)=CC=N4)C4=C1.O=P(O)(O)O.O=P(O)(O)O
CAS Number
173531-58-3
Target & IC50
Others
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Structure
Related Product Information for Naphthoquine phosphate, inhibitor
Naphthoquine phosphate is antimalarial drug.
References
Qu HY, et al. Single-dose safety, pharmacokinetics, and food effects studies of compound naphthoquine phosphate tablets in healthy volunteers. J Clin Pharmacol. 2010 Nov;50(11):1310-8.
Qu HY, et al. Single-dose safety, pharmacokinetics, and food effects studies of compound naphthoquine phosphate tablets in healthy volunteers. J Clin Pharmacol. 2010 Nov;50(11):1310-8.
Tun T, et al. Efficacy of oral single dose therapy with artemisinin-naphthoquine phosphate in uncomplicated falciparum malaria. Acta Trop. 2009 Sep;111(3):275-8.
Tun T, et al. Efficacy of oral single dose therapy with artemisinin-naphthoquine phosphate in uncomplicated falciparum malaria. Acta Trop. 2009 Sep;111(3):275-8.
Wang JY, et al. [Therapeutic efficacy of naphthoquine phosphate combined with artemisinine against Plasmodium knowlesi]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2008 Dec 30;26(6):442-444.
Wang JY, et al. [Therapeutic efficacy of naphthoquine phosphate combined with artemisinine against Plasmodium knowlesi]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2008 Dec 30;26(6):442-444.
Wang JY, et al. Naphthoquine phosphate and its combination with artemisinine. Acta Trop. 2004 Feb;89(3):375-81.
Wang JY, et al. Naphthoquine phosphate and its combination with artemisinine. Acta Trop. 2004 Feb;89(3):375-81.
Wang SQ, et al. Therapeutic effect of dihydroartemisinin combined with naphthoquine phosphate in patients with falciparum malaria.Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2002;20(3):180-2.
Wang SQ, et al. Therapeutic effect of dihydroartemisinin combined with naphthoquine phosphate in patients with falciparum malaria.Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2002;20(3):180-2.
El-Beshbishi SN, et al. First insight into the effect of single oral dose therapy with artemisinin-naphthoquine phosphate combination in a mouse model of Schistosoma mansoni infection. Int J Parasitol. 2013 Jun;43(7):521-530.
El-Beshbishi SN, et al. First insight into the effect of single oral dose therapy with artemisinin-naphthoquine phosphate combination in a mouse model of Schistosoma mansoni infection. Int J Parasitol. 2013 Jun;43(7):521-530.
Qu HY, et al. Single-dose safety, pharmacokinetics, and food effects studies of compound naphthoquine phosphate tablets in healthy volunteers. J Clin Pharmacol. 2010 Nov;50(11):1310-8.
Tun T, et al. Efficacy of oral single dose therapy with artemisinin-naphthoquine phosphate in uncomplicated falciparum malaria. Acta Trop. 2009 Sep;111(3):275-8.
Tun T, et al. Efficacy of oral single dose therapy with artemisinin-naphthoquine phosphate in uncomplicated falciparum malaria. Acta Trop. 2009 Sep;111(3):275-8.
Wang JY, et al. [Therapeutic efficacy of naphthoquine phosphate combined with artemisinine against Plasmodium knowlesi]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2008 Dec 30;26(6):442-444.
Wang JY, et al. [Therapeutic efficacy of naphthoquine phosphate combined with artemisinine against Plasmodium knowlesi]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2008 Dec 30;26(6):442-444.
Wang JY, et al. Naphthoquine phosphate and its combination with artemisinine. Acta Trop. 2004 Feb;89(3):375-81.
Wang JY, et al. Naphthoquine phosphate and its combination with artemisinine. Acta Trop. 2004 Feb;89(3):375-81.
Wang SQ, et al. Therapeutic effect of dihydroartemisinin combined with naphthoquine phosphate in patients with falciparum malaria.Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2002;20(3):180-2.
Wang SQ, et al. Therapeutic effect of dihydroartemisinin combined with naphthoquine phosphate in patients with falciparum malaria.Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2002;20(3):180-2.
El-Beshbishi SN, et al. First insight into the effect of single oral dose therapy with artemisinin-naphthoquine phosphate combination in a mouse model of Schistosoma mansoni infection. Int J Parasitol. 2013 Jun;43(7):521-530.
El-Beshbishi SN, et al. First insight into the effect of single oral dose therapy with artemisinin-naphthoquine phosphate combination in a mouse model of Schistosoma mansoni infection. Int J Parasitol. 2013 Jun;43(7):521-530.
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Product Notes
The Naphthoquine phosphate (Catalog #AAA5753553) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Naphthoquine phosphate, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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