Structure
MC-1568, Inhibitor
MC-1568
Purity
>98% (HPLC)
Synonyms
MC-1568; MC1568; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 18.5mg/mL
Target
HDAC
Receptor
HD1-A (Maize); HD1-B (Maize)
Chemical Name
2-Propenamide, 3-[5-[(1E)-3-(3-fluorophenyl)-3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-, (2E)
SMILES
O=C(NO)/C=C/C1=CC=C(/C=C/C(C2=CC=CC(F)=C2)=O)N1C
Molecular Formula
C17H15FN2O3
CAS Number
852475-26-4
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for MC-1568, inhibitor
A potent and selective class IIa HDAC inhibitor with IC50 of 220nM for maize HD1-A; displays 176-fold selectivity over HD1-B; increases the accumulation of acetylated H3 and H4 histones in MCF-7 cells at 20uM; promotes neurite growth and arbourisation and protects neurite arbours against neurotoxic insult.
Product Categories/Family for MC-1568, inhibitor
References
1. Mai A, et al. J Med Chem. 2005 May 5; 48 (9):3344-53.
2. Duong V, et al. Mol Cancer Res. 2008 Dec; 6 (12):1908-19.
3. Collins LM, et al. Mol Neurobiol. 2015; 51 (3):1432-42.
2. Duong V, et al. Mol Cancer Res. 2008 Dec; 6 (12):1908-19.
3. Collins LM, et al. Mol Neurobiol. 2015; 51 (3):1432-42.
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Product Notes
The MC-1568 (Catalog #AAA3606191) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MC-1568, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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