Structure
Lycobetaine acetate, Inhibitor
Lycobetaine acetate
Purity
98.00%
Synonyms
Lycobetaine acetate; Oxylycorine; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C18H15NO5
SMILES
CC([O-])=O.Oc1cc2CC[n+]3cc4cc5OCOc5cc4c(c1)c23
CAS Number
61221-41-8
Target & IC50
Others
Cell Research
The cytotoxicity, ferroptotic and necroptotic cell death were determined by the resazurin reduction assay. Caspase activation was evaluated using the caspase-Glo assay. Flow cytometry was applied for the analysis of cell cycle analysis (PI staining), apoptosis (annexin V/PI staining), mitochondrial membrane potential (MMP) (JC-1) and reactive oxygen species (ROS) (H2DCFH-DA). Apoptotic, necroptotic and autophagic markers were determined by Western blotting. CCRF-CEM leukemia cells were used for all mechanistic studies[1].
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Structure
Related Product Information for Lycobetaine acetate, inhibitor
Lycobetaine acetate is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Ungeremine have strong antibacterial activity against Flavobacterium columnare
References
Armelle T Mbaveng, Gabin T M Bitchagno, Victor Kuete,et al.Cytotoxicity of Ungeremine Towards Multi-Factorial Drug Resistant Cancer Cells and Induction of Apoptosis, Ferroptosis, Necroptosis and Autophagy.Phytomedicine. 2019 Jul;60:152832.
Armelle T Mbaveng, Gabin T M Bitchagno, Victor Kuete,et al.Cytotoxicity of Ungeremine Towards Multi-Factorial Drug Resistant Cancer Cells and Induction of Apoptosis, Ferroptosis, Necroptosis and Autophagy.Phytomedicine. 2019 Jul;60:152832.
Kevin K Schrader, Fabiana Avolio, Anna Andolfi.et alUngeremine and Its Hemisynthesized Analogues as Bactericides Against Flavobacterium Columnare.J Agric Food Chem. 2013 Feb 13;61(6):1179-83.
Kevin K Schrader, Fabiana Avolio, Anna Andolfi.et alUngeremine and Its Hemisynthesized Analogues as Bactericides Against Flavobacterium Columnare.J Agric Food Chem. 2013 Feb 13;61(6):1179-83.
Armelle T Mbaveng, Gabin T M Bitchagno, Victor Kuete,et al.Cytotoxicity of Ungeremine Towards Multi-Factorial Drug Resistant Cancer Cells and Induction of Apoptosis, Ferroptosis, Necroptosis and Autophagy.Phytomedicine. 2019 Jul;60:152832.
Kevin K Schrader, Fabiana Avolio, Anna Andolfi.et alUngeremine and Its Hemisynthesized Analogues as Bactericides Against Flavobacterium Columnare.J Agric Food Chem. 2013 Feb 13;61(6):1179-83.
Kevin K Schrader, Fabiana Avolio, Anna Andolfi.et alUngeremine and Its Hemisynthesized Analogues as Bactericides Against Flavobacterium Columnare.J Agric Food Chem. 2013 Feb 13;61(6):1179-83.
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Product Notes
The Lycobetaine acetate (Catalog #AAA5759141) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Lycobetaine acetate, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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