Structure
Indirubin, Inhibitor
Indirubin
Purity
>98% (HPLC)
Synonyms
Indirubin; C.I. 73200; Couroupitine B; NSC 105327; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=41mg/mL (156.33mM)
Target
Other Targets
Receptor
GSK-3beta , CDK2/CyclinA , CDK5/p35 , CDK1/CyclinB , C-Raf
Chemical Name
3-(1, 3-Dihydro-3-oxo-2H-indol-2-ylidene)-1, 3-dihydro-2H-indol-2-one
SMILES
C1=CC=C2C(=C1)/C(=C3/C(=O)C4=CC=CC=C4N3)/C(=O)N2
Molecular Formula
C16H10N2O2
CAS Number
479-41-4
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Indirubin, inhibitor
Indirubin is a potent and selective CDK inhibitor. Indirubin is the active ingredient of Danggui Longhui Wan, a mixture of plants that is used in traditional Chinese medicine to treat chronic diseases. Indirubin has been used to treat the symptoms of leukemia. Further biological explorations revealed the ability of indirubin to bind cyclin-dependent kinases and 6-bromoindirubin, extracted from mollusks, to bind glycogen synthase kinase-3. Studies have shown that Indirubin can help keep cancer cells from reproducing in rats. Indirubin also appears to reduce inflammation by inhibiting part of the immune response.
Product Categories/Family for Indirubin, inhibitor
References
1. Hoessel R, et al. Nat Cell Biol, 1999, 1 (1), 60-67.
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Product Notes
The Indirubin (Catalog #AAA3608596) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Indirubin, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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