Hexa-D-arginine, Inhibitor

Hexa-D-arginine

Cat. Num. AAA5758389

• Purity: 100.00%
• Synonyms: Hexa-D-arginine; inhibitor

• Purity/Purification: 100.00%
• Form/Format: Solid. Powder

• Solubility: H2O: 50mg/mL (52.40mM) Need ultrasonic; DMSO: 5mg/mL (5.24mM) Need ultrasonic; (<1mg/ml refers to the product slightly soluble or insoluble)
• Formula: C36H75N25O6
• SMILES: C(C[C@H](C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N)N)CN=C(N)N
• CAS Number: 673202-67-0
• Target & IC50: Furin: ic50 106nM (KI); PACE4: ic50 580nM (KI); PC1: ic50 13.2mM (ki)
• Preparation and Storage: Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent

Structure

Related Product Information for Hexa-D-arginine, inhibitor

Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.

References

Sarac M S, Cameron A, Lindberg I. The Furin Inhibitor Hexa-D-Arginine Blocks the Activation of Pseudomonas aeruginosa Exotoxin A In Vivo[J]. Infection and Immunity, 2002, 70(12):7136-7139.
Sarac M S, Cameron A, Lindberg I. The Furin Inhibitor Hexa-D-Arginine Blocks the Activation of Pseudomonas aeruginosa Exotoxin A In Vivo[J]. Infection and Immunity, 2002, 70(12):7136-7139.
Sarac M S, Peinado J R, Leppla S H, et al. Protection against Anthrax Toxemia by Hexa-D-Arginine In Vitro and In Vivo[J]. Infection and Immunity, 2004, 72(1):602-605.
Sarac M S, Peinado J R, Leppla S H, et al. Protection against Anthrax Toxemia by Hexa-D-Arginine In Vitro and In Vivo[J]. Infection and Immunity, 2004, 72(1):602-605.