Structure
Guanosine 5'-triphosphate trisodium salt, Inhibitor
Guanosine 5'-triphosphate trisodium salt
Purity
98.00%
Synonyms
Guanosine 5'-triphosphate trisodium salt; 5'-GTP trisodium salt; GTP Trisodium salt; inhibitor
Purity/Purification
98.00%
Form/Format
Powder
Formula
C10H15N5Na3O15P3
CAS
36051-31-7
Smiles
[Na+].[Na+].[Na+].Nc1nc(=O)c2ncn([C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O)c2[nH]1
Receptor (IC50)
Human Endogenous Metabolite
Solubility
Water: 50mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Structure
Structure
Related Product Information for Guanosine 5'-triphosphate trisodium salt, inhibitor
Guanosine 5'-triphosphate trisodium salt activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades.Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
References
1. Gutkind, Silvio J. Cell growth control by G protein-coupled receptors: from signal transduction to signal integration[J]. Oncogene, 1998, 17 (11):1331-1342.
2. Dhanasekaran N, Tsim S T, Dermott J M, et al. Regulation of cell proliferation by G proteins[J]. ONCOGENE, 1998, 17 (11):1383-1394.
3. J Gómez, C Martínez-A, A González, et al. Dual role of Ras and Rho proteins: at the cutting edge of life and death[J]. Immunology and Cell Biology, 1998, 76 (2):125-134.
2. Dhanasekaran N, Tsim S T, Dermott J M, et al. Regulation of cell proliferation by G proteins[J]. ONCOGENE, 1998, 17 (11):1383-1394.
3. J Gómez, C Martínez-A, A González, et al. Dual role of Ras and Rho proteins: at the cutting edge of life and death[J]. Immunology and Cell Biology, 1998, 76 (2):125-134.
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Product Notes
The Guanosine 5'-triphosphate trisodium salt (Catalog #AAA5751436) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Guanosine 5'-triphosphate trisodium salt, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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