Structure
Caffeic Acid Phenethyl Ester, Inhibitor
Caffeic Acid Phenethyl Ester
Purity
>98% (HPLC)
Synonyms
Caffeic Acid Phenethyl Ester; CAPE; beta-Phenylethyl Caffeate; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 150mg/mL (527.59mM)
Target
Other Targets
Receptor
NF-kappaB
Chemical Name
2-Phenylethyl(E)-3-(3, 4-dihydroxyphenyl)prop-2-enoate
SMILES
c1ccc(cc1)CCOC(=O)/C=C/c1ccc(c(c1)O)O
Molecular Formula
C17H16O4
CAS Number
104594-70-9
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Caffeic Acid Phenethyl Ester, inhibitor
Caffeic Acid Phenethyl Ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective and immunomodulating activities. CAPE is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1).
Product Categories/Family for Caffeic Acid Phenethyl Ester, inhibitor
References
1. Natarajan K, et al. Proc Natl Acad Sci U S A. 1996, 93 (17), 9090-9095.
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Product Notes
The Caffeic Acid Phenethyl Ester (Catalog #AAA3607773) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Caffeic Acid Phenethyl Ester, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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