Bisabolol oxide A, Inhibitor
Bisabolol oxide A
Purity
98.00%
Synonyms
Bisabolol oxide A; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C15H26O2
SMILES
CC(C)([C@H](CC1)O)O[C@]1(C)[C@@H]1CC=C(C)CC1
CAS Number
22567-36-8
Target & IC50
Others
In Vitro
In present study, the cytotoxic effect ofmicroMolar BSBO was cytometrically examined on rat thymocytes by using appropriate fluorescent dyes. When the cells were incubated with BSBO for 24 hours, BSBO at concentrations of 30microM or more significantly increased populations of dead cells, shrunken cells, and cells with phosphatidylserine exposed on membrane surface. Both cell shrinkage and externalization of membrane phosphatidylserine are general features in an early stage of apoptosis. In addition, BSBO significantly increased population of cells containing hypodiploid DNA, and the increase was completely attenuated by Z-VAD-FMK, a pan-inhibitor for caspases, indicating an involvement of caspase activation[1]
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Bisabolol oxide A, inhibitor
Bisabololoxide A induces apoptosis in rat thymocytes.
References
Bisabololoxide A, one of the main constituents in German chamomile extract, induces apoptosis in rat thymocytes. Arch Toxicol. 2010 Jan;84(1):45-52.
Bisabololoxide A, one of the main constituents in German chamomile extract, induces apoptosis in rat thymocytes. Arch Toxicol. 2010 Jan;84(1):45-52.
Cytotoxic action of bisabololoxide A of German chamomile on human leukemia K562 cells in combination with 5-fluorouracilPhytomedicine. 2011 Mar 15;18(5):362-5.
Bisabololoxide A, one of the main constituents in German chamomile extract, induces apoptosis in rat thymocytes. Arch Toxicol. 2010 Jan;84(1):45-52.
Cytotoxic action of bisabololoxide A of German chamomile on human leukemia K562 cells in combination with 5-fluorouracilPhytomedicine. 2011 Mar 15;18(5):362-5.
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Product Notes
The Bisabolol oxide A (Catalog #AAA5760189) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Bisabolol oxide A, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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