Chemical Structure
Berbamine, Inhibitor
Berbamine
Purity
98.00%
Synonyms
Berbamine; CaMKII inhibitor; inhibitor
Purity/Purification
98.00%
Form/Format
POWDER
CAS Number
478-61-5
Formula
C37H40N2O6
Smiles
COc1cc2CCN(C)[C@H]3Cc4ccc(Oc5cc(C[C@H]6N(C)CCc7cc(OC)c(OC)c(Oc1cc23)c67)ccc5O)cc4
Solubility
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble; DMSO: Soluble
Pathways
Neuroscience
Receptor
CAMKIIgamma
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
In Solvent: 2 years -80 degree C
Chemical Structure
Chemical Structure
Related Product Information for Berbamine, inhibitor
1. Berbamine has high binding affinity toward the (GGA); G-quadruplex. 2. Berbamine and its derivatives are promising agents to suppress liver cancer growth by targeting CAMKII. 3. Berbamine may be the first ATP-competitive inhibitor of CaMKII gamma, could be as a new type of molecular targeted agent through inhibition of the CaMKII gamma activity for treatment of leukemia. 4. Berbamine can enhance the antitumor activity of gemcitabine by inhibiting cell growth and inducing apoptosis, possibly through the regulation of the expression of apoptosis-related proteins and the activation of TGF-beta/Smad signaling pathway. 5. Berbamine confers cardioprotection against I/R injury by attenuating [Ca(2+)inf(i) overloading and preventing calpain activation through the activation of the PI3K-Akt-GSK3beta pathway and, subsequently, opening of the mitoK(ATP) channel.
Product Categories/Family for Berbamine, inhibitor
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Product Notes
The Berbamine (Catalog #AAA5750320) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Berbamine, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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