Structure
Bafilomycin A1, Inhibitor
Bafilomycin A1
Purity
>98% (HPLC)
Synonyms
Bafilomycin A1; NSC 381866; inhibitor
Purity/Purification
>98% (HPLC)
Target
Proton Pump
Chemical Name
(3E, 5E, 7R, 8S, 9S, 11E, 13Z, 15S)-16-((2S, 3R, 4S)-4-((2R, 4R, 5S, 6R)-2, 4-dihydroxy-6-isopropyl-5-methyltetrahydro-2H-pyran-2-yl)-3-hydroxypentan-2-yl)-8-hydroxy-3, 15-dimethoxy-5, 7, 9, 11-tetramethyloxacyclohexadeca-3, 5, 11, 13-tetraen-2-one
SMILES
O[C@H]([C@H](C)/C=C(C)/C=C1OC)[C@@H](C)C/C(C)=C/C=C[C@H](OC)C([C@@H](C)[C@H]([C@@H]([C@@]2(O)C[C@@H](O)[C@H](C)[C@@H]([C@H](C)C)O2)C)O)OC/1=O
Molecular Formula
C??H??O?
CAS Number
88899-55-2
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Bafilomycin A1, inhibitor
Bafilomycin A1 is a macrolide antibiotic isolated from the Streptomyces species and an inhibitor of vacuolar V-ATPase.
Product Categories/Family for Bafilomycin A1, inhibitor
References
1. Yuan N, et al. Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia. Haematologica. 2015 Mar; 100 (3):345-56.
2. Lu X, et al. Bafilomycin A1 inhibits the growth and metastatic potential of the BEL-7402 liver cancer and HO-8910 ovarian cancer cell lines and induces alterations in their microRna expression. Exp Ther Med. 2015 Nov; 10 (5):1829-1834.
2. Lu X, et al. Bafilomycin A1 inhibits the growth and metastatic potential of the BEL-7402 liver cancer and HO-8910 ovarian cancer cell lines and induces alterations in their microRna expression. Exp Ther Med. 2015 Nov; 10 (5):1829-1834.
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Product Notes
The Bafilomycin A1 (Catalog #AAA3606417) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Bafilomycin A1, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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