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Chemical Structure (Asunaprevir is an inhibitor of the viral enzyme serine protease NS3.)

Asunaprevir (BMS-650032), Inhibitor

Asunaprevir (BMS-650032)

Purity
>98%
Synonyms
Asunaprevir (BMS-650032); BMS650032; ASV; inhibitor
Ordering
For Research Use Only!
Purity/Purification
>98%
Form/Format
Powder
Concentration
0.1 mM: 13.36 mL (1 mg); 66.82 mL (5 mg); 133.64mL (10 mg)
0.5 mM: 2.67 mL (1 mg); 13.36 mL (5 mg); 26.73 mL (10 mg)
1 mM: 1.34 mL (1 mg); 6.68 mL (5 mg); 13.36 mL (10 mg)
5 mM: 0.27 mL (1 mg); 1.34 mL (5 mg); 2.67 mL (10 mg) (varies by lot)
CAS Number
630420-16-5
Formula
C35H46ClN5O9S
SMILES
O=C(N[C@@]1(C(NS(C2CC2)(=O)=O)=O)[C@H](C=C)C1)[C@H]3N(C([C@H](C(C)(C)C)NC(OC(C)(C)C)=O)=O)C[C@@H](OC4=C(C=C(Cl)C=C5)C5=C(OC)C=N4)C3
Actions
Inhibitor
Availability
We cannot ship this item to Switzerland, Italy, Germany, France and Austria.
Preparation and Storage
at -20 degree C 3 years Powder

Chemical Structure

(Asunaprevir is an inhibitor of the viral enzyme serine protease NS3.)

Chemical Structure (Asunaprevir is an inhibitor of the viral enzyme serine protease NS3.)
Related Product Information for Asunaprevir (BMS-650032), inhibitor
Asunaprevir is an inhibitor of the viral enzyme serine protease NS3.
References
Fay EJ, .et al. Engineered Small-Molecule Control of Influenza A Virus Replication, J Virol, 2018, Fay EJ PMID: 30282710
Bennie Lemmens, .et al. DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation, Mol Cell, 2018, Jul 5; 71(1): 117-128.e3 PMID: 30008317
Ueda Y, .et al. Evaluation of preclinical antimalarial drugs, which can overcome direct-acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems, Virus Res, 2017, May 2;235:37-48 PMID: 28322919
Furihata T, .et al. Differential inhibition features of direct-acting anti-hepatitis C virus agents against human organic anion transporting polypeptide 2B1, Int J Antimicrob Agents, 2015, Oct;46(4):381-8 PMID: 26163159
Tomomi Furihata, .et al. Different Interaction Profiles of Direct-Acting Anti-Hepatitis C Virus Agents with Human Organic Anion Transporting Polypeptides, Antimicrob Agents Chemother, 2014, 58(8): 4555-4564. PMID: 24867984

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Product Notes

The Asunaprevir (BMS-650032) (Catalog #AAA384395) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Asunaprevir (BMS-650032), Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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