Mouse interphotoreceptor matrix proteoglycan 2 ELISA Kit | IMPG2 elisa kit
Mouse Interphotoreceptor matrix proteoglycan 2, IMPG2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
IMPG2: Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light- sensitive photoreceptor outer segment. Binds heparin. Defects in IMPG2 are the cause of retinitis pigmentosa type 56 (RP56). RP56 is a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. Defects in IMPG2 are the cause of maculopathy IMPG2- related (MACLP-IMPG2). MACLP-IMPG2 is a mild maculopathy characterized by full-field electroretinogram responses within normal limits, normal color vision, elevation of the photoreceptor layer in the foveal region and mild nuclear sclerosis.
Protein type: Membrane protein, integral; Extracellular matrix
Cellular Component: proteinaceous extracellular matrix; membrane; integral to membrane; receptor complex
Molecular Function: heparin binding; hyaluronic acid binding
Research Articles on IMPG2
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Product Notes
The Mouse IMPG2 impg2 (Catalog #AAA9329795) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9329795 ELISA Kit recognizes Mouse IMPG2. It is sometimes possible for the material contained within the vial of "interphotoreceptor matrix proteoglycan 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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