Interleukin 7 (IL7) Recombinant Protein | IL7 recombinant protein

Recombinant Interleukin 7 (IL7)

Cat. Num. AAA2010810

• Gene Names: Il7; Il-7; hlb368; A630026I06Rik
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Interleukin 7 (IL7); Recombinant Interleukin 7 (IL7); IL7 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.; MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGS-ECHIK DKEGKAYESV LMISIDELDK MTGTDSNCPN NEPNFFRKHV CDDTKEAAFL NRAARKLKQF LKMNISEEFN VHLLTVSQGT QTLVNCTSKE EKNVKEQKKN DACFLKRLLR EIKTCWNKIL KGSI
• Sequence Length: 154

• Applicable Applications for IL7 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Mus musculus (Mouse)
• Expression System: Prokaryotic expression
• Residues: Glu26~Ile154 (Accession # P10168) with N-terminal His-Tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

NCBI and Uniprot Product Information

• NCBI GI #: 6680433
• NCBI GeneID: 16196
• NCBI Accession #: NP_032397.1
• NCBI GenBank Nucleotide #: NM_008371.4
• UniProt Accession #: P10168
• Molecular Weight: 18.4kDa
• NCBI Official Full Name: interleukin-7
• NCBI Official Synonym Full Names: interleukin 7
• NCBI Official Symbol: Il7
• NCBI Official Synonym Symbols: Il-7; hlb368; A630026I06Rik
• NCBI Protein Information: interleukin-7
• UniProt Protein Name: Interleukin-7
• Protein Family: Interleukin
• UniProt Gene Name: Il7
• UniProt Synonym Gene Names: Il-7; IL-7
• UniProt Entry Name: IL7_MOUSE

NCBI Description

The protein encoded by this gene is a hematopoietic growth factor important for B and T cell development. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Uniprot Description

IL7: Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Cell development/differentiation; Apoptosis; Cell cycle regulation; Secreted, signal peptide; Cytokine

Cellular Component: extracellular space; extracellular region

Molecular Function: interleukin-7 receptor binding; growth factor activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; cytokine activity

Biological Process: organ morphogenesis; T cell lineage commitment; cell-cell signaling; positive regulation of T cell differentiation; homeostasis of number of cells within a tissue; regulation of gene expression; negative regulation of catalytic activity; positive regulation of B cell proliferation; immune response; positive regulation of organ growth; humoral immune response; bone resorption