Interleukin 13 Receptor Alpha 1 (IL13Ra1) Recombinant Protein | IL13Ra1 recombinant protein

Recombinant Interleukin 13 Receptor Alpha 1 (IL13Ra1)

Cat. Num. AAA2009429

• Gene Names: Il13ra1; NR4; Il13ra; CD213a1; AI882074; IL-13r[a]
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Interleukin 13 Receptor Alpha 1 (IL13Ra1); Recombinant Interleukin 13 Receptor Alpha 1 (IL13Ra1); IL13Ra1 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.; MGHHHHHHSGSEF-EVQ PPVTNLSVSV ENLCTIIWTW SPPEGASPNC TLRYFSHFDD QQDKKIAPET HRKEELPLDE KICLQVGSQC SANESEKPSP LVKKCISPPE GDPESAVTEL KCIWHNLSYM KCSWLPGRNT SPDTHYTLYY WYSSLEKSRQ C
• Sequence Length: 424

• Applicable Applications for IL13Ra1 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Mus musculus (Mouse)
• Expression System: Prokaryotic expression
• Residues: Glu28~Cys171 (Accession # O09030) with N-terminal His-Tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 40254373
• NCBI GeneID: 16164
• NCBI Accession #: NP_598751.3
• NCBI GenBank Nucleotide #: NM_133990.4
• UniProt Accession #: O09030; Q7TT27
• Molecular Weight: 18.0kDa
• NCBI Official Full Name: interleukin-13 receptor subunit alpha-1
• NCBI Official Synonym Full Names: interleukin 13 receptor, alpha 1
• NCBI Official Symbol: Il13ra1
• NCBI Official Synonym Symbols: NR4; Il13ra; CD213a1; AI882074; IL-13r[a]
• NCBI Protein Information: interleukin-13 receptor subunit alpha-1; IL-13RA1; IL-13R-alpha-1; IL-13R subunit alpha-1; novel cytokine receptor 4; IL-13 receptor subunit alpha-1; interleukin-13-binding protein
• UniProt Protein Name: Interleukin-13 receptor subunit alpha-1
• Protein Family: Interleukin-13 receptor
• UniProt Gene Name: Il13ra1
• UniProt Synonym Gene Names: Il13r; Il13ra; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; NR4
• UniProt Entry Name: I13R1_MOUSE

NCBI Description

This gene encodes a transmembrane protein that complexes with interleukin 4 receptor alpha (IL4RA) to form a functional receptor for interleukin-13. Signalling through this pathway mediates allergy response and occurs during bronchial asthma. [provided by RefSeq, May 2015]

Uniprot Description

IL13R: Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. Belongs to the type I cytokine receptor family. Type 5 subfamily.

Protein type: Membrane protein, integral; Receptor, cytokine

Cellular Component: membrane; integral to membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-13 receptor activity