Porcine Interleukin 29 ELISA Kit | IL-29 elisa kit

Porcine Interleukin 29 ELISA Kit

Cat. Num. AAA43283

• Gene Names: IFNL1; IL29; IL-29
• Reactivity: Porcine
• Synonyms: Interleukin 29; Porcine Interleukin 29 ELISA Kit; IL-29 elisa kit

• Reactivity: Porcine
• Sequence Length: 200

• Assay Type: Quantitative Sandwich
• Detection Range: 31.2pg/ml-1000pg/ml
• Sensitivity: 5.0pg/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for IL-29 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of IL29 (hereafter termed "analyte") in undiluted original Porcine serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 26024325
• NCBI GeneID: 282618
• NCBI Accession #: NP_742152.1
• NCBI GenBank Nucleotide #: NM_172140.1
• UniProt Accession #: Q8IU54; Q17R34; A0AV25
• Molecular Weight: 21,898 Da
• NCBI Official Full Name: interferon lambda-1
• NCBI Official Synonym Full Names: interferon, lambda 1
• NCBI Official Symbol: IFNL1
• NCBI Official Synonym Symbols: IL29; IL-29
• NCBI Protein Information: interferon lambda-1; IFN-lambda-1; interleukin-29; cytokine Zcyto21; interferon-lambda-1; interleukin 29 (interferon, lambda 1)
• UniProt Protein Name: Interferon lambda-1
• UniProt Gene Name: IFNL1
• UniProt Synonym Gene Names: IL29; ZCYTO21; IFN-lambda-1; IL-29
• UniProt Entry Name: IFNL1_HUMAN

NCBI Description

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]

Uniprot Description

IL29: Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the IL-28/IL-29 family.

Protein type: Secreted; Secreted, signal peptide; Cell cycle regulation; Cytokine

Chromosomal Location of Human Ortholog: 19q13.13

Cellular Component: extracellular space; extracellular region; interleukin-28 receptor complex

Molecular Function: cytokine activity; interleukin-28 receptor binding; receptor binding

Biological Process: positive regulation of immune response; positive regulation of transcription, DNA-dependent; positive regulation of JAK-STAT cascade; JAK-STAT cascade; negative regulation of T cell differentiation; negative regulation of cell proliferation; negative regulation of interleukin-13 production; positive regulation of interferon-gamma production; negative regulation of T-helper 2 type immune response; positive regulation of tyrosine phosphorylation of STAT protein; negative regulation of interleukin-5 production; positive regulation of MHC class I biosynthetic process; negative regulation of memory T cell differentiation; negative regulation of transcription, DNA-dependent; defense response to virus