Mouse IKAROS family zinc finger 1 (Ikaros) ELISA Kit | IKZF1 elisa kit
Mouse DNA-binding protein Ikaros, IKZF1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Ikaros: a transcription factor of the ikaros C2H2-type zinc-finger protein family. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Functions in the specification and the maturation of the T-lymphocyte. Also interacts with a critical control element in the TDT (terminal deoxynucleotidyltransferase) promoter as well as with the promoters for other genes expressed during early stages of B- and T-cell development. Deletions in Ikaros have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Seven alternatively spliced human isoforms have been described.
Protein type: DNA-binding; Transcription factor; C2H2-type zinc finger protein
Cellular Component: centric heterochromatin; transcription factor complex; protein complex; cytoplasm; nucleus
Molecular Function: protein binding; nucleic acid binding; DNA binding; protein heterodimerization activity; sequence-specific DNA binding; metal ion binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; Peyer's patch development; gland development; thymus development; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of multicellular organism growth; chromatin modification; cell cycle; lymph node development; regulation of transcription from RNA polymerase II promoter; positive regulation of neutrophil differentiation; regulation of transcription, DNA-dependent; retina development in camera-type eye; natural killer cell differentiation; B cell differentiation; forebrain development; positive regulation of B cell differentiation; positive regulation of NK T cell differentiation; hemopoiesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; T cell differentiation
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Product Notes
The Mouse IKZF1 ikzf1 (Catalog #AAA9333580) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9333580 ELISA Kit recognizes Mouse IKZF1. It is sometimes possible for the material contained within the vial of "IKAROS family zinc finger 1 (Ikaros), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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