DNA-binding protein SMUBP-2 (IGHMBP2) Recombinant Protein | IGHMBP2 recombinant protein

Recombinant Human DNA-binding protein SMUBP-2 (IGHMBP2) , partial

Cat. Num. AAA951564

• Gene Names: IGHMBP2; HCSA; HMN6; CATF1; CMT2S; SMARD1; SMUBP2; ZFAND7
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: DNA-binding protein SMUBP-2 (IGHMBP2); Recombinant Human DNA-binding protein SMUBP-2 (IGHMBP2); partial; IGHMBP2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 646-884. Partial
• Sequence: IVPENYSHENSQGSSHAATKPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFE

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 119392094
• NCBI GeneID: 3508
• NCBI Accession #: NP_002171.2
• NCBI GenBank Nucleotide #: NM_002180.2
• UniProt Accession #: P38935; Q00443; Q14177; A0PJD2
• Molecular Weight: 109,149 Da
• NCBI Official Full Name: DNA-binding protein SMUBP-2
• NCBI Official Synonym Full Names: immunoglobulin mu binding protein 2
• NCBI Official Symbol: IGHMBP2
• NCBI Official Synonym Symbols: HCSA; HMN6; CATF1; CMT2S; SMARD1; SMUBP2; ZFAND7
• NCBI Protein Information: DNA-binding protein SMUBP-2
• UniProt Protein Name: DNA-binding protein SMUBP-2
• Protein Family: DNA-binding protein
• UniProt Gene Name: IGHMBP2
• UniProt Synonym Gene Names: SMBP2; SMUBP2; GF-1

NCBI Description

This gene encodes a helicase superfamily member that binds a specific DNA sequence from the immunoglobulin mu chain switch region. Mutations in this gene lead to spinal muscle atrophy with respiratory distress type 1. [provided by RefSeq, Jul 2008]

Uniprot Description

5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation (). DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV.