Interferon gamma receptor 2 (IFNGR2) Recombinant Protein | IFNGR2 recombinant protein
Recombinant Human Interferon gamma receptor 2 (IFNGR2), partial
NCBI and Uniprot Product Information
NCBI Description
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008]
Uniprot Description
Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:8124716, PubMed:7673114,PubMed:7615558). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:8124716, PubMed:7673114, PubMed:15356148). Required for signal transduction in contrast to other receptor subunit responsible for ligand binding (PubMed:7673114).
Research Articles on IFNGR2
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Product Notes
The IFNGR2 ifngr2 (Catalog #AAA949799) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 28-247. Partial, provide the complete extracellular domain. The amino acid sequence is listed below: SQLPAPQHPK IRLYNAEQVL SWEPVALSNS TRPVVYQVQF KYTDSKWFTA DIMSIGVNCT QITATECDFT AASPSAGFPM DFNVTLRLRA ELGALHSAWV TMPWFQHYRN VTVGPPENIE VTPGEGSLII RFSSPFDIAD TSTAFFCYYV HYWEKGGIQQ VKGPFRSNSI SLDNLKPSRV YCLQVQAQLL WNKSNIFRVG HLSNISCYET MADASTELQQ . It is sometimes possible for the material contained within the vial of "Interferon gamma receptor 2 (IFNGR2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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