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Interferon beta Recombinant Protein | IFNB1 recombinant protein

Interferon beta, Recombinant, Mouse (CHO) (IFNb)

Gene Names
IFNB1; IFB; IFF; IFNB; MGC96956
Purity
Purified
Purified
Synonyms
Interferon beta; Recombinant; Mouse (CHO) (IFNb); IFNB1 recombinant protein
Ordering
For Research Use Only!
Host
Mouse, CHO-derived
Purity/Purification
Purified
Purified
Form/Format
Supplied as a lyophilized powder in PBS, 10% mouse albumin, 0.01% gelatin. Reconstitute the vial by injection of 1 ml distilled or de-ionized water (Caution: vial is under vacuum).
Application Notes
Dilution: For dilutions use a buffer containing 2% bovine serum albumin or culture medium. (Do not use fresh serum.)
Preparation and Storage
Lyophilized powder may be stored at-20 degree C. Stable for 12 months at -20 degree C. Reconstitute with 1ml distilled or de-ionized water. Aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. Note: mouse IFN-beta is highly labile when agitated.
Related Product Information for IFNB1 recombinant protein
Three types of interferons have been described: interferon-alpha (IFN-alpha), interferon-beta (IFN-beta), and interferon-gamma (IFN-gamma). An extensive variety of biological effects have been observed for the interferon family including antiviral activity; anti-proliferative activity; stimulation of cytotoxic activities in lymphocytes, natural killer cells, and macrophages; and modulation of the major histocompatibility complex. Only one mouse-IFN-beta gene has yet been described. It codes for a 161 amino acid polypeptide (20kD). Mouse-IFN-beta binds to the type I interferon receptor. It is not recognized by antibodies directed against mouse

One unit of mouse beta interferon is the amount of beta interferon which protects 50% of the indicator cell population from viral destruction. One unit of Mouse Beta Interferon approximates the bioactivity contained in one unit of the mouse beta interferon standard prepared by NIH (Gb02-902-511).
Product Categories/Family for IFNB1 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,294 Da
NCBI Official Full Name
interferon beta
NCBI Official Synonym Full Names
interferon, beta 1, fibroblast
NCBI Official Symbol
IFNB1
NCBI Official Synonym Symbols
IFB; IFF; IFNB; MGC96956
NCBI Protein Information
interferon beta; IFN-beta; OTTHUMP00000021131; fibroblast interferon
UniProt Protein Name
Interferon beta
Protein Family
UniProt Gene Name
IFNB1
UniProt Synonym Gene Names
IFB; IFNB
UniProt Entry Name
IFNB_HUMAN

Uniprot Description

Function: Has antiviral, antibacterial and anticancer activities.

Subunit structure: Monomer.

Subcellular location: Secreted.

Pharmaceutical use: Available under the names Avonex (Biogen), Betaseron (Berlex) and Rebif (Serono). Used in the treatment of multiple sclerosis (MS). Betaseron is a slightly modified form of IFNB1 with two residue substitutions.

Sequence similarities: Belongs to the alpha/beta interferon family.

Research Articles on IFNB1

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Product Notes

The IFNB1 ifnb1 (Catalog #AAA650588) is a Recombinant Protein produced from Mouse, CHO-derived and is intended for research purposes only. The product is available for immediate purchase. Dilution: For dilutions use a buffer containing 2% bovine serum albumin or culture medium. (Do not use fresh serum.). Researchers should empirically determine the suitability of the IFNB1 ifnb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Interferon beta, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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