Human interferon-induced protein with tetratricopeptide repeats 2 ELISA Kit | IFIT2 elisa kit
Human Interferon-induced protein with tetratricopeptide repeats 2, IFIT2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
IFIT2: IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O- methylation (cap snatching mechanism). Can promote apoptosis. Belongs to the IFIT family.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 10q23.31
Cellular Component: endoplasmic reticulum; cytoplasm; cytosol
Molecular Function: protein binding
Biological Process: apoptotic mitochondrial changes; positive regulation of apoptosis; cytokine and chemokine mediated signaling pathway; response to virus; negative regulation of protein binding; defense response to virus
Research Articles on IFIT2
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Product Notes
The Human IFIT2 ifit2 (Catalog #AAA9331904) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331904 ELISA Kit recognizes Human IFIT2. It is sometimes possible for the material contained within the vial of "interferon-induced protein with tetratricopeptide repeats 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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