Bovine Indoleamine 2,3-Dioxygenase ELISA Kit | IDO elisa kit
Bovine Indoleamine 2,3-Dioxygenase ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Catalyzes the first step in tryptophan catabolism in order to supply de novo nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway. Plays a role in the cellular response to telomere uncapping.
Catalytic activity: D-tryptophan + O2 = N-formyl-D-kynurenine.L-tryptophan + O2 = N-formyl-L-kynurenine.
Cofactor: Binds 1 heme group per subunit
By similarity.
Pathway: Cofactor biosynthesis; NAD(+) biosynthesis. Ref.4
Induction: Expression is mediated by the AFT2, HCM1, and SUM1 transcription factors. Up-regulated in absence of NPT1.
Miscellaneous: Present with 149 molecules/cell in log phase SD medium.
Sequence similarities: Belongs to the indoleamine 2,3-dioxygenase family.
Biophysicochemical propertiesKinetic parameters:KM=412 µM for L-tryptophanKM=9.2 mM for D-tryptophan
Research Articles on IDO
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Product Notes
The Bovine IDO bna2 (Catalog #AAA028821) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA028821 ELISA Kit recognizes Bovine IDO. It is sometimes possible for the material contained within the vial of "Indoleamine 2,3-Dioxygenase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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