Thyroxine Binding Globulin (TBG) Protein | TBG protein
Thyroxine Binding Globulin (TBG)
Gene Names
SERPINA7; TBG
Purity
>= 98% (SDS-PAGE)
Synonyms
Thyroxine Binding Globulin (TBG); Serpin A7; T4-binding globulin; TBG; TBG protein
Host
Human Serum
Purity/Purification
>= 98% (SDS-PAGE)
Form/Format
Lyophilized from 20 mM ammonium bicarbonate. May contain traces of buffer salts.
Protein
Reported in mg/vial (A280, E0.1%=0.9)
Appearance
White lyophilized solid
Related Product Information for TBG protein
Human Thyroxine Binding Globulin (TBG) is one of three proteins responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3-triiodothyronine (T3) in the bloodstream, along with transthyretin and albumin.
TBG has the highest affinity for T4 and T3, but is present in the lowest concentration of the three proteins. Despite the low concentration, it carries the majority of T4 in serum.
Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with ligand. Unlike transthyretin and albumin, Thyroxin Binding Globulin has a single binding site for T4/T3.
TBG has the highest affinity for T4 and T3, but is present in the lowest concentration of the three proteins. Despite the low concentration, it carries the majority of T4 in serum.
Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with ligand. Unlike transthyretin and albumin, Thyroxin Binding Globulin has a single binding site for T4/T3.
Product Categories/Family for TBG protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,000
NCBI Official Full Name
thyroxine-binding globulin
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
NCBI Official Symbol
SERPINA7
NCBI Official Synonym Symbols
TBG
NCBI Protein Information
thyroxine-binding globulin; serpin A7; T4-binding globulin; thyroxin-binding globulin; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
UniProt Protein Name
Thyroxine-binding globulin
UniProt Gene Name
SERPINA7
UniProt Synonym Gene Names
TBG
UniProt Entry Name
THBG_HUMAN
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Product Notes
The TBG serpina7 (Catalog #AAA173673) is a Protein produced from Human Serum and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Thyroxine Binding Globulin (TBG), Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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