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CD200R recombinant antibody

Anti-CD200R [OX108]

Gene Names
CD200R1; OX2R; MOX2R; CD200R; HCRTR2
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Protein A Affinity Purified
Synonyms
CD200R; Anti-CD200R [OX108]; CD200 Cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; CD200R1; OX2R; CD200 receptor-like 2; HuCD200R2; CD200RLa; CD200R recombinant antibody
Ordering
For Research Use Only!
Reactivity
Human
Isotype
Mouse IgG1, kappa
Clone Number
OX108
Specificity
Recognizes human CD200R, a receptor for the CD200/OX2.
Purity/Purification
Protein A Affinity Purified
Sequence Length
325
Applicable Applications for CD200R recombinant antibody
Flow Cytometry (FC/FACS)
Buffer Composition
PBS only with 0.02% Proclin 300.
Immunogen
Recombinant protein - hCD200RCD4d3+4.
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
Related Product Information for CD200R recombinant antibody
Recombinant monoclonal antibody to CD200R. Manufactured using a Recombinant Platform with variable regions (i.e. specificity) from the hybridoma OX108.
Product Categories/Family for CD200R recombinant antibody
References
Wright GJ, Cherwinski H, Foster-Cuevas M, Brooke G, Puklavec MJ, Bigler M, Song Y, Jenmalm M, Gorman D, McClanahan T, Liu MR, Brown MH, Sedgwick JD, Phillips JH, Barclay AN. Characterization of the CD200 receptor family in mice and humans and their interactions with CD200. J Immunol. 2003 Sep 15; 171(6):3034-46.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
39,056 Da
NCBI Official Full Name
Cell surface glycoprotein CD200 receptor 1
NCBI Official Synonym Full Names
CD200 receptor 1
NCBI Official Symbol
CD200R1
NCBI Official Synonym Symbols
OX2R; MOX2R; CD200R; HCRTR2
NCBI Protein Information
cell surface glycoprotein CD200 receptor 1
UniProt Protein Name
Cell surface glycoprotein CD200 receptor 1
UniProt Gene Name
CD200R1
UniProt Synonym Gene Names
CD200R; CRTR2; MOX2R; OX2R
UniProt Entry Name
MO2R1_HUMAN

NCBI Description

This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Uniprot Description

CD200R: Receptor for the CD200/OX2 cell surface glycoprotein. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. Belongs to the CD200R family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 3q13.2

Cellular Component: external side of plasma membrane; plasma membrane; receptor complex

Molecular Function: protein binding; receptor activity

Biological Process: regulation of immune response

Research Articles on CD200R

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Product Notes

The CD200R cd200r1 (Catalog #AAA488073) is a Recombinant Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD200R [OX108] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD200R can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CD200R cd200r1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD200R, Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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