anti-Human, Rat TAF1A Antibody | anti-TAF1A antibody

TAF1A Antibody

Cat. Num. AAA8509775

• Gene Names: TAF1A; SL1; RAFI48; TAFI48; MGC:17061
• Reactivity: Human, Rat
• Applications: Western Blot, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: TAF1A; TAF1A Antibody; TATA box-binding protein-associated factor 1A; TBP-associated factor 1A; TBP-associated factor RNA polymerase I 48 kDa; TAFI48; Transcription factor SL1; anti-TAF1A antibody

• Reactivity: Human, Rat
• Specificity: TAF1A antibody detects endogenous levels of total TAF1A protein.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 450

• Applicable Applications for anti-TAF1A antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500~1:1000; ELISA: 1:5000
• Immunogen: The antiserum was produced against synthesized peptide derived from internal of human TAF1A.
• Preparation and Storage: Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from HeLa cells, using TAF1A antibody.)

References

Comai L., Science 266:1966-1972(1994). Ota T., Nat. Genet. 36:40-45(2004). Gregory S.G., Nature 441:315-321(2006).

NCBI and Uniprot Product Information

• NCBI GI #: 319996599
• NCBI GeneID: 9015
• NCBI Accession #: NP_001188465.1
• NCBI GenBank Nucleotide #: NM_001201536.1
• UniProt Accession #: Q15573; Q9NWA1; B2RDZ8; D3DTB7
• Molecular Weight: 39,615 Da
• NCBI Official Full Name: TATA box-binding protein-associated factor RNA polymerase I subunit A isoform 1
• NCBI Official Synonym Full Names: TATA-box binding protein associated factor, RNA polymerase I subunit A
• NCBI Official Symbol: TAF1A
• NCBI Official Synonym Symbols: SL1; RAFI48; TAFI48; MGC:17061
• NCBI Protein Information: TATA box-binding protein-associated factor RNA polymerase I subunit A
• UniProt Protein Name: TATA box-binding protein-associated factor RNA polymerase I subunit A
• Protein Family: TATA box-binding protein-associated factor
• UniProt Gene Name: TAF1A
• UniProt Synonym Gene Names: TAFI48; TBP-associated factor 1A

NCBI Description

This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.[provided by RefSeq, Jan 2011]

Uniprot Description

Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.