Troponin I Native Protein | TNNI3 native protein
Troponin I protein (Cardiac)
Applications
User optimized
Purity
> 98% pure
Synonyms
Troponin I; Troponin I protein (Cardiac); TNNI3 native protein
Host
Human
Purity/Purification
> 98% pure
Form/Format
Lyophilized from 0.01 M HCl. Reconstitute with Urea Tris buffer, pH7.5, (7M Urea, 5mM EDTA, 15mM mercaptoethanol, 20mM Tris).
Sequence Length
211
Applicable Applications for TNNI3 native protein
User optimized
Source Note
Human heart tissue
Protein Type
Native
Biological Significance
Human troponin I is presented in cardiac muscle tissue by a single isoform with molecular weight 23876 Da and it consists of 209 amino acid residues. cTnI molecule contains two serines in the 22 and 23 positions. Both amino acid residues can be phosphorylated in vivo by protein kinase A, so four forms of protein ? one dephospho, two monophospho and one bisphospho ? can coexist in the cell.
Biohazard Information
Donor samples were tested and found to be negative for HBsAg, HIV-1 and HIV-2 antibodies, HCV, and syphilis. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Aliquot and store at -20 degree C for short term storage, -70 degree C for long-term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for TNNI3 native protein
Purified native Human Troponin I protein (Cardiac)
Product Categories/Family for TNNI3 native protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,912 Da
NCBI Official Full Name
troponin I, cardiac muscle
NCBI Official Symbol
TNNI3
NCBI Protein Information
troponin I, cardiac muscle
UniProt Protein Name
Troponin I, cardiac muscle
Protein Family
UniProt Gene Name
TNNI3
UniProt Entry Name
TNNI3_CANFA
Uniprot Description
TNNI3: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Binds to actin and tropomyosin. Interacts with TRIM63. Interacts with STK4/MST1. Belongs to the troponin I family.
Protein type: Actin-binding; Motility/polarity/chemotaxis; Motor
Research Articles on TNNI3
Similar Products
Product Notes
The TNNI3 tnni3 (Catalog #AAA537590) is a Native Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Troponin I can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the TNNI3 tnni3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Troponin I, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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