TIMP1 native protein

Purified native Human TIMP1 protein

Cat. Num. AAA5308407

• Gene Names: TIMP1; EPA; EPO; HCI; CLGI; TIMP; TIMP-1
• Purity: Purified using a proprietary chromatographic technique.
• Synonyms: TIMP1; Purified native Human TIMP1 protein; TIMP1 protein; TIMP1 native protein

• Host: Human
• Purity/Purification: Purified using a proprietary chromatographic technique.
• Form/Format: Supplied in 50 mM Tris-HCl, pH 7; 200 mM NaCl; 5 mM CaCl2; 1 uM ZnCl2; 0.05% Brij 35; 0,05% NaN3
• Sequence Length: 207

• Source Note: Human Neutrophil Granulocytes
• Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
• Preparation and Storage: Store at -80 degree C.

Western Blot (WB)

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Product Categories/Family for TIMP1 native protein

Proteases; Inhibitors; & Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 49456917
• NCBI GeneID: 7076
• UniProt Accession #: Q6FGX5; P01033
• Molecular Weight: 23,171 Da
• NCBI Official Full Name: TIMP1
• NCBI Official Synonym Full Names: TIMP metallopeptidase inhibitor 1
• NCBI Official Symbol: TIMP1
• NCBI Official Synonym Symbols: EPA; EPO; HCI; CLGI; TIMP; TIMP-1
• NCBI Protein Information: metalloproteinase inhibitor 1
• UniProt Protein Name: TIMP metallopeptidase inhibitor 1, isoform CRA_a
• Protein Family: Metalloproteinase inhibitor
• UniProt Gene Name: TIMP1

NCBI Description

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]