FABP native protein

FABP protein

Cat. Num. AAA537009

• Gene Names: FABP7; MRG; BLBP; FABPB; B-FABP; LTR2-FABP7
• Applications: User optimized
• Purity: > 95% pure
• Synonyms: FABP; FABP protein; Fatty Acid Binding Protein; FABP native protein

• Host: Human
• Purity/Purification: > 95% pure
• Form/Format: Lyophilized from 10 mM Tris-HCl, pH 8.0. Reconstitute in distilled water.
• Sequence Length: 132

• Applicable Applications for FABP native protein: User optimized
• Source Note: Human cardiac muscle tissue
• Protein Type: Native
• Biological Significance: FABP is a newly introduced plasma marker of acute myocardial infarction (AMI). The plasma kinetics of FABP (15 kDa) closely resemble those of myoglobin in that elevated plasma concentrations are found within 2 hours after AMI and return to normal generally within 18 to 24 hours. FABP is a useful biochemical marker for the early assessment or exclusion of AMI. FABP also appears to be a useful plasma marker for the estimation of myocardial infarct size.
• Biohazard Information: Donor samples were tested and found to be negative for HBsAg, HIV-1 and HIV-2 antibodies, HCV, and syphilis. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
• Preparation and Storage: Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles

Related Product Information for FABP native protein

Purified native Human FABP protein

Product Categories/Family for FABP native protein

Cardiac Markers; Native Protein

NCBI and Uniprot Product Information

• NCBI GI #: 2645203
• NCBI GeneID: 2173
• UniProt Accession #: O15540; O14951; Q6IAU7; Q9H047; B2R4L1
• Molecular Weight: 18,829 Da
• NCBI Official Full Name: fatty acid binding protein
• NCBI Official Synonym Full Names: fatty acid binding protein 7, brain
• NCBI Official Symbol: FABP7
• NCBI Official Synonym Symbols: MRG; BLBP; FABPB; B-FABP; LTR2-FABP7
• NCBI Protein Information: fatty acid-binding protein, brain
• UniProt Protein Name: Fatty acid-binding protein, brain
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP7
• UniProt Synonym Gene Names: BLBP; FABPB; MRG; BLBP; B-FABP
• UniProt Entry Name: FABP7_HUMAN

NCBI Description

The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]

Uniprot Description

FABP7: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding; Cell development/differentiation; Cell cycle regulation

Chromosomal Location of Human Ortholog: 6q22-q23

Cellular Component: cell projection; cell soma; cytoplasm; nucleus

Molecular Function: transporter activity; lipid binding

Biological Process: nervous system development; negative regulation of cell proliferation; epithelial cell proliferation; neurogenesis; prepulse inhibition; transport; cell proliferation in forebrain