Sequence Information
Substance P (SP) Small Molecule | SP small molecule
OVA Conjugated Substance P (SP)
Sequence Information
Sequence Information
SDS-Page
SDS-Page
NCBI and Uniprot Product Information
NCBI Description
mediates neuropeptide signaling; may play a role in pain sensitivity; may mediate baroreflex transmission for blood pressure regulation [RGD, Feb 2006]
Uniprot Description
TACR1: This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 4q34
Cellular Component: cell surface; cytoplasm; dendrite; integral component of membrane; plasma membrane
Molecular Function: substance P receptor activity
Biological Process: acute inflammatory response; angiotensin mediated drinking behavior; associative learning; behavioral response to pain; eating behavior; elevation of cytosolic calcium ion concentration; learning and/or memory; long-term memory; neuropeptide signaling pathway; operant conditioning; positive regulation of action potential; positive regulation of blood pressure; positive regulation of epithelial cell proliferation; positive regulation of hormone secretion; positive regulation of leukocyte migration; positive regulation of lymphocyte proliferation; positive regulation of ossification; positive regulation of saliva secretion; positive regulation of stress fiber formation; positive regulation of synaptic transmission, cholinergic; positive regulation of synaptic transmission, GABAergic; positive regulation of vascular permeability; positive regulation of vasoconstriction; regulation of blood pressure; regulation of smooth muscle cell migration; regulation of smooth muscle cell proliferation; response to electrical stimulus; response to estradiol; response to ethanol; response to heat; response to hormone; response to morphine; response to nicotine; response to organic cyclic compound; response to ozone; response to pain; response to progesterone; sensory perception of pain; smooth muscle contraction involved in micturition; sperm ejaculation; tachykinin signaling pathway
Research Articles on SP
Similar Products
Product Notes
The SP tacr1 (Catalog #AAA2097369) is a Small Molecule and is intended for research purposes only. The product is available for immediate purchase. The OVA Conjugated Substance P (SP) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Substance P (SP) can be used in a range of immunoassay formats including, but not limited to, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the SP tacr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Substance P (SP), Small Molecule" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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