Testing Data
(The TFact MYC DNA-Binding ELISA detects active MYC in Jurkat Nuclear Extract. The Jurkat cells were grown 3 days in RPMI 1640 with 10% FBS and harvested for nuclear extract.)
MYC elisa kit
MYC TFact DNA-Binding ELISA Kit
Testing Data
(The TFact MYC DNA-Binding ELISA detects active MYC in Jurkat Nuclear Extract. The Jurkat cells were grown 3 days in RPMI 1640 with 10% FBS and harvested for nuclear extract.)
Testing Data
(The TFact MYC DNA-Binding ELISA detects active MYC in Jurkat Nuclear Extract. The Jurkat cells were grown 3 days in RPMI 1640 with 10% FBS and harvested for nuclear extract.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Uniprot Description
Myc: a proto-oncogenic transcription factor that plays a role in cell proliferation, apoptosis and in the development of human tumors. Seems to activate the transcription of growth-related genes.
Protein type: DNA-binding; Nucleolus; Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 8q24.21
Cellular Component: cytosol; nuclear chromatin; nucleolus; nucleoplasm; nucleus; protein complex
Molecular Function: activating transcription factor binding; DNA binding; DNA binding transcription factor activity; protein binding; protein complex binding; protein dimerization activity; transcription factor binding
Biological Process: beta-catenin-TCF complex assembly; branching involved in ureteric bud morphogenesis; cell cycle arrest; cellular iron ion homeostasis; cellular response to DNA damage stimulus; cellular response to hypoxia; cellular response to UV; chromatin remodeling; chromosome organization and biogenesis; energy reserve metabolic process; ERK1 and ERK2 cascade; fibroblast apoptotic process; G1/S transition of mitotic cell cycle; MAPK cascade; negative regulation of apoptosis; negative regulation of cell division; negative regulation of fibroblast proliferation; negative regulation of monocyte differentiation; negative regulation of stress-activated MAPK cascade; negative regulation of transcription from RNA polymerase II promoter; Notch signaling pathway; oxygen transport; positive regulation of cell proliferation; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of DNA biosynthetic process; positive regulation of epithelial cell proliferation; positive regulation of fibroblast proliferation; positive regulation of gene expression; positive regulation of mesenchymal cell proliferation; positive regulation of metanephric cap mesenchymal cell proliferation; positive regulation of response to DNA damage stimulus; positive regulation of telomerase activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; protein deubiquitination; protein-DNA complex disassembly; regulation of gene expression; regulation of telomere maintenance; regulation of transcription from RNA polymerase II promoter; response to drug; response to gamma radiation; transcription from RNA polymerase II promoter; Wnt receptor signaling pathway through beta-catenin
Disease: Burkitt Lymphoma
Research Articles on MYC
Similar Products
Product Notes
The Human, Mouse, Rat MYC myc (Catalog #AAA9502212) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502212 ELISA Kit recognizes Human, Mouse, Rat MYC. It is sometimes possible for the material contained within the vial of "MYC, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
