Testing Data
(The TFact MYB (Phospho-Ser12) DNA-Binding ELISA detects active MYB (Phospho-Ser12) in Hela and Jurkat Nuclear Extract. The Hela and Jurkat cells were grown 3 days in DMEM and RPMI 1640 with 10% FBS and harvested for nuclear extract.)
MYB elisa kit
MYB (Phospho-Ser12) TFact DNA-Binding ELISA Kit
Testing Data
(The TFact MYB (Phospho-Ser12) DNA-Binding ELISA detects active MYB (Phospho-Ser12) in Hela and Jurkat Nuclear Extract. The Hela and Jurkat cells were grown 3 days in DMEM and RPMI 1640 with 10% FBS and harvested for nuclear extract.)
Testing Data
(The TFact MYB (Phospho-Ser12) DNA-Binding ELISA detects active MYB (Phospho-Ser12) in Hela and Jurkat Nuclear Extract. The Hela and Jurkat cells were grown 3 days in DMEM and RPMI 1640 with 10% FBS and harvested for nuclear extract.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Uniprot Description
Myb: Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 6q23.3
Cellular Component: nuclear matrix; nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: cellular response to hydrogen peroxide; cellular response to retinoic acid; chromatin remodeling; mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of collagen biosynthetic process; positive regulation of hepatic stellate cell activation; positive regulation of hepatic stellate cell proliferation; positive regulation of histone H3-K4 methylation; positive regulation of histone H3-K9 methylation; positive regulation of neuron apoptotic process; positive regulation of smooth muscle cell proliferation; positive regulation of T-helper cell differentiation; positive regulation of testosterone secretion; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; positive regulation of transforming growth factor beta production; regulation of hematopoietic stem cell differentiation; regulation of transcription, DNA-templated; response to hypoxia; transcription from RNA polymerase II promoter
Research Articles on MYB
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Product Notes
The Human, Mouse, Rat MYB myb (Catalog #AAA9502206) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502206 ELISA Kit recognizes Human, Mouse, Rat MYB. It is sometimes possible for the material contained within the vial of "MYB, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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