Testing Data
(The TFact KLF10/11 DNA-Binding ELISA detects active KLF10/11 in MCF7 Nuclear Extract. The MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. )
KLF10/11 elisa kit
KLF10/11 TFact DNA-Binding ELISA Kit
Testing Data
(The TFact KLF10/11 DNA-Binding ELISA detects active KLF10/11 in MCF7 Nuclear Extract. The MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. )
Testing Data
(The TFact KLF10/11 DNA-Binding ELISA detects active KLF10/11 in MCF7 Nuclear Extract. The MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. )
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Uniprot Description
KLF10: Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth. Binds to the consensus sequence 5'-GGTGTG-3'. Belongs to the Sp1 C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 8q22.3
Cellular Component: nucleus
Molecular Function: DNA binding transcription factor activity; metal ion binding; protein binding
Biological Process: bone mineralization; cell proliferation; cell-cell signaling; cellular response to starvation; circadian rhythm; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of osteoclast differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of circadian rhythm; skeletal system development; somatic stem cell maintenance; transcription from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway
Research Articles on KLF10/11
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Product Notes
The Human, Mouse, Rat KLF10/11 klf10 (Catalog #AAA9502305) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502305 ELISA Kit recognizes Human, Mouse, Rat KLF10/11. It is sometimes possible for the material contained within the vial of "KLF10/11, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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