GAB2 elisa kit
Phospho-Gab2 (Ser623) Colorimetric Cell-Based ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
Uniprot Description
GAB2: an adaptor protein of the GRB2-associated binding protein family. Plays important roles in regulating the growth, differentiation, and function of many hematopoietic cell types.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 11q14.1
Cellular Component: cytoplasm; cytosol; plasma membrane
Molecular Function: phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; protein binding; transmembrane receptor protein tyrosine kinase adaptor protein activity
Biological Process: axon guidance; Fc-epsilon receptor signaling pathway; osteoclast differentiation; phosphoinositide-mediated signaling; positive regulation of cell proliferation; positive regulation of mast cell degranulation; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on GAB2
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Product Notes
The Human, Mouse, Rat GAB2 gab2 (Catalog #AAA9501677) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9501677 ELISA Kit recognizes Human, Mouse, Rat GAB2. It is sometimes possible for the material contained within the vial of "Gab2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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