Testing Data
(The TFact FOXH1 DNA-Binding ELISA detects active FOXH1 in Hela Nuclear Extract. The Hela cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. The Hela cells were Serum stimulated (20% FBS) before harvest.)
FOXH1 elisa kit
FOXH1 TFact DNA-Binding ELISA Kit
Testing Data
(The TFact FOXH1 DNA-Binding ELISA detects active FOXH1 in Hela Nuclear Extract. The Hela cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. The Hela cells were Serum stimulated (20% FBS) before harvest.)
Testing Data
(The TFact FOXH1 DNA-Binding ELISA detects active FOXH1 in Hela Nuclear Extract. The Hela cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. The Hela cells were Serum stimulated (20% FBS) before harvest.)
NCBI and Uniprot Product Information
NCBI Description
FOXH1 encodes a human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 protein binds SMAD2 and activates an activin response element via binding the DNA motif TGT(G/T)(T/G)ATT. [provided by RefSeq, Jul 2008]
Uniprot Description
FOXH1: Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
Protein type: DNA-binding; Nuclear receptor co-regulator; Transcription factor
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: nuclear chromatin; nucleoplasm; nucleus; transcription factor complex
Molecular Function: androgen receptor binding; bHLH transcription factor binding; DNA binding; DNA binding transcription factor activity; protein binding; protein domain specific binding; sequence-specific DNA binding; SMAD binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Biological Process: anatomical structure morphogenesis; axial mesoderm development; cell differentiation; embryonic heart tube anterior/posterior pattern formation; heart looping; negative regulation of estrogen receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; transcription from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway
Disease: Holoprosencephaly 1
Research Articles on FOXH1
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Product Notes
The Human, Mouse, Rat FOXH1 foxh1 (Catalog #AAA9502175) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502175 ELISA Kit recognizes Human, Mouse, Rat FOXH1. It is sometimes possible for the material contained within the vial of "FOXH1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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