Testing Data
(The TFact B-Myb (Phospho-Ser577/581) DNA-Binding ELISA detects active B-Myb (Phospho-Ser577/581) in HepG2 and MCF7 Nuclear Extract. The HepG2 and MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract.)
B-Myb elisa kit
B-Myb (Phospho-Ser577/581) TFact DNA-Binding ELISA Kit
Testing Data
(The TFact B-Myb (Phospho-Ser577/581) DNA-Binding ELISA detects active B-Myb (Phospho-Ser577/581) in HepG2 and MCF7 Nuclear Extract. The HepG2 and MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract.)
Testing Data
(The TFact B-Myb (Phospho-Ser577/581) DNA-Binding ELISA detects active B-Myb (Phospho-Ser577/581) in HepG2 and MCF7 Nuclear Extract. The HepG2 and MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
Uniprot Description
B-Myb: a transcription factor involved in cell cycle progression. Phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
Protein type: DNA-binding; Motility/polarity/chemotaxis; Transcription factor
Chromosomal Location of Human Ortholog: 20q13.12
Cellular Component: nucleoplasm; nucleus
Molecular Function: DNA binding transcription factor activity; protein binding
Biological Process: cell differentiation; mitotic spindle assembly; positive regulation of neuron apoptotic process; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
Research Articles on B-Myb
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Product Notes
The Human, Mouse, Rat B-Myb mybl2 (Catalog #AAA9502296) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502296 ELISA Kit recognizes Human, Mouse, Rat B-Myb. It is sometimes possible for the material contained within the vial of "B-Myb, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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