VTI1A Antibody | anti-VTI1A antibody

VTI1A Antibody

Cat. Num. AAA8515313

• Gene Names: VTI1A; MMDS3; MVti1; VTI1RP2; Vti1-rp2
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Immunogen affinity purified
• Synonyms: VTI1A; VTI1A Antibody; Vesicle transport through interaction with t-SNAREs homolog 1A; Vesicle transport v-SNARE protein Vti1-like 2; Vti1-rp2; anti-VTI1A antibody

• Reactivity: Human, Mouse, Rat
• Specificity: VTI1A Antibody detects endogenous levels of total VTI1A
• Purity/Purification: Immunogen affinity purified
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 224

• Applicable Applications for anti-VTI1A antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthesized peptide
• Preparation and Storage: Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts from 3T3 cells, using VTI1A antibody.)

NCBI and Uniprot Product Information

• NCBI GI #: 970598264
• NCBI GeneID: 143187
• NCBI Accession #: NP_001305132.1
• NCBI GenBank Nucleotide #: NM_001318203.1
• UniProt Accession #: Q96AJ9; Q5W0D7; A2A307; B4E137
• Molecular Weight: 23 KD
• NCBI Official Full Name: vesicle transport through interaction with t-SNAREs homolog 1A isoform a
• NCBI Official Synonym Full Names: vesicle transport through interaction with t-SNAREs 1A
• NCBI Official Symbol: VTI1A
• NCBI Official Synonym Symbols: MMDS3; MVti1; VTI1RP2; Vti1-rp2
• NCBI Protein Information: vesicle transport through interaction with t-SNAREs homolog 1A
• UniProt Protein Name: Vesicle transport through interaction with t-SNAREs homolog 1A
• Protein Family: Vesicle transport through interaction with t-SNAREs
• UniProt Gene Name: VTI1A

NCBI Description

The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Uniprot Description

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence.