Western Blot (WB)
(Western blot analysis of extracts from HeLa cells and HepG2 cells, using PKP2 antibody.)
PKP2 Antibody | anti-PKP2 antibody
PKP2 Antibody
Gene Names
PKP2; ARVD9
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
PKP2; PKP2 Antibody; Plakophilin-2; anti-PKP2 antibody
Reactivity
Human, Mouse, Rat
Specificity
PKP2 antibody detects endogenous levels of total PKP2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
837
Applicable Applications for anti-PKP2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:20000
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human PKP2.
Preparation and Storage
Store at-20 degree C for 1 year.
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells and HepG2 cells, using PKP2 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells and HepG2 cells, using PKP2 antibody.)
Product Categories/Family for anti-PKP2 antibody
References
Mertens C., J. Cell Biol. 135:1009-1025(1996). Rikova K., Cell 131:1190-1203(2007). Matsuoka S., Science 316:1160-1166(2007).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
92,756 Da
NCBI Official Full Name
plakophilin-2 isoform 2a
NCBI Official Synonym Full Names
plakophilin 2
NCBI Official Symbol
PKP2
NCBI Official Synonym Symbols
ARVD9
NCBI Protein Information
plakophilin-2
UniProt Protein Name
Plakophilin-2
Protein Family
UniProt Gene Name
PKP2
NCBI Description
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008]
Uniprot Description
May play a role in junctional plaques.
Research Articles on PKP2
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Product Notes
The PKP2 pkp2 (Catalog #AAA854272) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The PKP2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PKP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:20000. Researchers should empirically determine the suitability of the PKP2 pkp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PKP2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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