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Western Blot (WB) (Western blot analysis of extracts from COLO205 cells, using MAEA antibody.)

MAEA Antibody | anti-MAEA antibody

MAEA Antibody

Gene Names
MAEA; EMP; EMLP; GID9; PIG5; HLC-10
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
MAEA; MAEA Antibody; Macrophage erythroblast attacher; Erythroblast macrophage protein; Cell proliferation-inducing gene 5 protein; Lung cancer-related protein 10; HLC-10; EMP; HLC10; PIG5; anti-MAEA antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
MAEA antibody detects endogenous levels of total MAEA protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
396
Applicable Applications for anti-MAEA antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human MAEA.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from COLO205 cells, using MAEA antibody.)

Western Blot (WB) (Western blot analysis of extracts from COLO205 cells, using MAEA antibody.)
References
Ota T., Nat. Genet. 36:40-45(2004). Hanspal M., Blood 92:2940-2950(1998). Bala S., Biochem. Biophys. Res. Commun. 342:1040-1048(2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,802 Da
NCBI Official Full Name
macrophage erythroblast attacher isoform 1
NCBI Official Synonym Full Names
macrophage erythroblast attacher
NCBI Official Symbol
MAEA
NCBI Official Synonym Symbols
EMP; EMLP; GID9; PIG5; HLC-10
NCBI Protein Information
macrophage erythroblast attacher
UniProt Protein Name
Macrophage erythroblast attacher
UniProt Gene Name
MAEA
UniProt Synonym Gene Names
EMP; HLC-10

NCBI Description

This gene encodes a protein that mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. The encoded protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Uniprot Description

Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.

Research Articles on MAEA

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Product Notes

The MAEA maea (Catalog #AAA852245) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The MAEA Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAEA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:20000. Researchers should empirically determine the suitability of the MAEA maea for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAEA, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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