Western Blot (WB)
(Western blot analysis on 293 and HepG2 cell lysate using M3K13 Antibody)
M3K13 Antibody | anti-M3K13 antibody
M3K13 Antibody
Gene Names
MAP3K13; LZK; MLK; MEKK13
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity-chromatography
Synonyms
M3K13; M3K13 Antibody; Leucine zipper-bearing kinase; LZK; MAP3K13; MEKK13; MGC133196; Mitogen-activated protein kinase kinase kinase 13; Mixed lineage kinase; MLK; anti-M3K13 antibody
Reactivity
Human, Mouse, Rat
Specificity
M3K13 antibody detects endogenous levels of total M3K13
Purity/Purification
Affinity-chromatography
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
966
Applicable Applications for anti-M3K13 antibody
Western Blot (WB)
Application Notes
WB: 1:500~1:3000
Immunogen
A synthesized peptide derived from human M3K13
Preparation and Storage
Store at-20 degree C for 1 year
Western Blot (WB)
(Western blot analysis on 293 and HepG2 cell lysate using M3K13 Antibody)
Western Blot (WB)
(Western blot analysis on 293 and HepG2 cell lysate using M3K13 Antibody)
Related Product Information for anti-M3K13 antibody
LZK a TKL kinase of the MLK family. Synergizes with antioxidant protein-1 to activate NF-kappaB. Forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway. This kinase can phosphorylate and activate JNK and MKK7.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
108kDa
NCBI Official Full Name
mitogen-activated protein kinase kinase kinase 13 isoform 1
NCBI Official Synonym Full Names
mitogen-activated protein kinase kinase kinase 13
NCBI Official Symbol
MAP3K13
NCBI Official Synonym Symbols
LZK; MLK; MEKK13
NCBI Protein Information
mitogen-activated protein kinase kinase kinase 13
UniProt Protein Name
Mitogen-activated protein kinase kinase kinase 13
UniProt Gene Name
MAP3K13
UniProt Synonym Gene Names
MLK
NCBI Description
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq, Jul 2008]
Uniprot Description
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
Research Articles on M3K13
Similar Products
Product Notes
The M3K13 map3k13 (Catalog #AAA8510817) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The M3K13 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's M3K13 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500~1:3000. Researchers should empirically determine the suitability of the M3K13 map3k13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "M3K13, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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