Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

KPB1/2 Antibody | anti-KPB1/2 antibody

KPB1/2 Antibody

Gene Names
PHKA2; PHK; PYK; XLG; PYKL; XLG2; GSD9A
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
KPB1/2; KPB1/2 Antibody; GSD9A; KPB2; MGC133071; PHK; PHKA2; PHKLA; phosphorylase b kinase regulatory subunit alpha liver isoform; Phosphorylase b kinase regulatory subunit alpha; liver isoform; Phosphorylase kinase alpha L subunit; phosphorylase kinase alpha-subunit; phosphorylase kinase; alpha 2 (liver); PYK; PYKL; XLG; XLG2; KPB1; MGC132604; PHKA; PHKA1; phosphorylase b kinase regulatory subunit alpha skeletal muscle isoform; skeletal muscle isoform; Phosphorylase kinase alpha M subunit; alpha 1 (muscle); muscle glycogenosis; anti-KPB1/2 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
KPB1/2 antibody detects endogenous levels of total KPB1/2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1235
Applicable Applications for anti-KPB1/2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:3000
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human KPB1/2.
Preparation and Storage
Store at-20 degree C for 1 year.
References
van den Berg I.E.T., Am. J. Hum. Genet. 56:381-387(1995). Hirono H., Biochem. Mol. Biol. Int. 36:505-511(1995). Hendrickx J., Am. J. Hum. Genet. 64:1541-1549(1999).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
138,408 Da
NCBI Official Full Name
phosphorylase b kinase regulatory subunit alpha, liver isoform
NCBI Official Synonym Full Names
phosphorylase kinase regulatory subunit alpha 2
NCBI Official Symbol
PHKA2
NCBI Official Synonym Symbols
PHK; PYK; XLG; PYKL; XLG2; GSD9A
NCBI Protein Information
phosphorylase b kinase regulatory subunit alpha, liver isoform
UniProt Protein Name
Phosphorylase b kinase regulatory subunit alpha, liver isoform
UniProt Gene Name
PHKA2
UniProt Synonym Gene Names
PHKLA; PYK; Phosphorylase kinase alpha L subunit

NCBI Description

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.[provided by RefSeq, Feb 2010]

Uniprot Description

Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

Research Articles on KPB1/2

Similar Products

Product Notes

The KPB1/2 phka2 (Catalog #AAA859191) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The KPB1/2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KPB1/2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:3000 ELISA: 1:10000. Researchers should empirically determine the suitability of the KPB1/2 phka2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KPB1/2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.