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Testing Data (Peptide-+)

JAK1 Antibody | anti-JAK1 antibody

JAK1 Antibody

Gene Names
JAK1; JTK3; JAK1A; JAK1B
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
JAK1; JAK1 Antibody; EC 2.7.10.2; JAK-1; JAK1A; Janus kinase 1; kinase Jak1; anti-JAK1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
JAK1 antibody detects endogenous levels of total JAK1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1154
Applicable Applications for anti-JAK1 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
IF: 1:100-1:500
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human JAK1.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

(Peptide-+)

Testing Data (Peptide-+)

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JAK1 antibody. Immunofluorescence analysis of HeLa cells, using JAK1 antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JAK1 antibody. Immunofluorescence analysis of HeLa cells, using JAK1 antibody.)
References
Wilks A.F., Mol. Cell. Biol. 11:2057-2065(1991). Lee S.-T., Oncogene 8:3403-3410(1993). Lindholm C.K., Biochem. Biophys. Res. Commun. 296:929-936(2002).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
133,277 Da
NCBI Official Full Name
tyrosine-protein kinase JAK1 isoform 1
NCBI Official Synonym Full Names
Janus kinase 1
NCBI Official Symbol
JAK1
NCBI Official Synonym Symbols
JTK3; JAK1A; JAK1B
NCBI Protein Information
tyrosine-protein kinase JAK1
UniProt Protein Name
Tyrosine-protein kinase JAK1
Protein Family
UniProt Gene Name
JAK1
UniProt Synonym Gene Names
JAK1A; JAK1B; JAK-1

NCBI Description

This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Uniprot Description

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529).

Research Articles on JAK1

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Product Notes

The JAK1 jak1 (Catalog #AAA855545) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The JAK1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's JAK1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). IHC: 1:50-1:100 IF: 1:100-1:500 ELISA: 1:10000. Researchers should empirically determine the suitability of the JAK1 jak1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JAK1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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