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Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using IBP7 antibody.)

IBP7 Antibody | anti-IBP7 antibody

IBP7 Antibody

Gene Names
IGFBP7; AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
IBP7; IBP7 Antibody; Insulin-like growth factor-binding protein 7 [Precursor]; IGFBP-7; IBP-7; IGF-binding protein 7; MAC25 protein; Prostacyclin-stimulating factor; PGI2-stimulating factor; IGFBP-rP1; IGFBP7; MAC25; PSF; anti-IBP7 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
IBP7 antibody detects endogenous levels of total IBP7 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
279
Applicable Applications for anti-IBP7 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human IBP7.
Preparation and Storage
Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using IBP7 antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using IBP7 antibody.)
References
Murphy M., Cell Growth Differ. 4:715-722(1993). Yamauchi T., Biochem. J. 303:591-598(1994). Oh Y., J. Biol. Chem. 271:30322-30325(1996).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,860 Da
NCBI Official Full Name
insulin-like growth factor-binding protein 7 isoform 2
NCBI Official Synonym Full Names
insulin like growth factor binding protein 7
NCBI Official Symbol
IGFBP7
NCBI Official Synonym Symbols
AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1
NCBI Protein Information
insulin-like growth factor-binding protein 7
UniProt Protein Name
Insulin-like growth factor-binding protein 7
UniProt Gene Name
IGFBP7
UniProt Synonym Gene Names
MAC25; PSF; IBP-7; IGF-binding protein 7; IGFBP-7; TAF

NCBI Description

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]

Uniprot Description

Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.

Research Articles on IBP7

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Product Notes

The IBP7 igfbp7 (Catalog #AAA8509828) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The IBP7 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IBP7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:40000. Researchers should empirically determine the suitability of the IBP7 igfbp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IBP7, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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