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Immunohistochemistry (IHC) (Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FGFR1 Oncogene Partner antibody.)

FGFR1 Oncogene Partner Antibody | anti-FGFR1 antibody

FGFR1 Oncogene Partner Antibody

Gene Names
FGFR1OP; FOP
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
FGFR1 Oncogene Partner; FGFR1 Oncogene Partner Antibody; FOP; FIBROBLAST GROWTH FACTOR RECEPTOR 1 ONCOGENE PARTNER; anti-FGFR1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
FGFR1 Oncogene Partner antibody detects endogenous levels of total FGFR1 Oncogene Partner protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
399
Applicable Applications for anti-FGFR1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from human FGFR1 Oncogene Partner.
Preparation and Storage
Store at-20 degree C for 1 year

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FGFR1 Oncogene Partner antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FGFR1 Oncogene Partner antibody.)

Western Blot (WB)

(Western blot analysis of extracts from HepG2 cells, using FGFR1 Oncogene Partner antibody.)

Western Blot (WB) (Western blot analysis of extracts from HepG2 cells, using FGFR1 Oncogene Partner antibody.)
References
Asuman Demiroglu, Blood, Dec 2001; 98: 3778-3783. Géraldine Guasch, Blood, Jan 2003; 101: 286-288. Ronald Simon, Cancer Res., Jun 2001; 61: 4514-4519. Ute Schell, Hum. Mol. Genet., Mar 1995; 4: 323-328.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,106 Da
NCBI Official Full Name
FGFR1 oncogene partner isoform a
NCBI Official Synonym Full Names
FGFR1 oncogene partner
NCBI Official Symbol
FGFR1OP
NCBI Official Synonym Symbols
FOP
NCBI Protein Information
FGFR1 oncogene partner
UniProt Protein Name
FGFR1 oncogene partner
Protein Family
UniProt Gene Name
FGFR1OP
UniProt Synonym Gene Names
FOP

NCBI Description

This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]

Uniprot Description

Required for anchoring microtubules to the centrosomes (PubMed:16314388, PubMed:28659385). Required for ciliation (PubMed:28625565, PubMed:28659385).

Research Articles on FGFR1

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Product Notes

The FGFR1 fgfr1op (Catalog #AAA852129) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The FGFR1 Oncogene Partner Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FGFR1 Oncogene Partner can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000. Researchers should empirically determine the suitability of the FGFR1 fgfr1op for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FGFR1 Oncogene Partner, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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