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Western Blot (WB) (Western blot analysis of extracts from HepG2 cells, using DNAJB4 antibody.)

DNAJB4 Antibody | anti-DNAJB4 antibody

DNAJB4 Antibody

Gene Names
DNAJB4; DjB4; HLJ1; DNAJW
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
DNAJB4; DNAJB4 Antibody; DJB4; DnaJ homolog subfamily B member 4; DNAJW; DNJB4; Heat shock 40 kDa protein 1 homolog; Heat shock protein 40 homolog; HLJ1; HSP40 homolog; anti-DNAJB4 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
DNAJB4 antibody detects endogenous levels of total DNAJB4 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
337
Applicable Applications for anti-DNAJB4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human DNAJB4.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from HepG2 cells, using DNAJB4 antibody.)

Western Blot (WB) (Western blot analysis of extracts from HepG2 cells, using DNAJB4 antibody.)
References
Hoe K.L., Biochim. Biophys. Acta 1383:4-8(1998). The MGC Project Team; Genome Res. 14:2121-2127(2004). Rush J., Nat. Biotechnol. 23:94-101(2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,807 Da
NCBI Official Full Name
dnaJ homolog subfamily B member 4 isoform a
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member B4
NCBI Official Symbol
DNAJB4
NCBI Official Synonym Symbols
DjB4; HLJ1; DNAJW
NCBI Protein Information
dnaJ homolog subfamily B member 4
UniProt Protein Name
DnaJ homolog subfamily B member 4
Protein Family
UniProt Gene Name
DNAJB4
UniProt Synonym Gene Names
DNAJW; HLJ1; HSP40 homolog; Heat shock protein 40 homolog

NCBI Description

The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Uniprot Description

Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877).

Research Articles on DNAJB4

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Product Notes

The DNAJB4 dnajb4 (Catalog #AAA856247) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The DNAJB4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DNAJB4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:40000. Researchers should empirically determine the suitability of the DNAJB4 dnajb4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNAJB4, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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