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Testing Data (Peptide-+)

DNAJB11 Antibody | anti-DNAJB11 antibody

DNAJB11 Antibody

Gene Names
DNAJB11; DJ9; EDJ; Dj-9; ERj3; ABBP2; ERdj3; ERj3p; ABBP-2; UNQ537; PRO1080
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
DNAJB11; DNAJB11 Antibody; ABBP-2; ABBP2; DJB11; DnaJ (Hsp40) homolog; subfamily B; member 11; DNJBB; EDJ; ER-associated Hsp40 co-chaperone; ERJ3; anti-DNAJB11 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
DNAJB11 antibody detects endogenous levels of total DNAJB11 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
358
Applicable Applications for anti-DNAJB11 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human DNAJB11.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

(Peptide-+)

Testing Data (Peptide-+)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human heart tissue using DNAJB11 antibody. Western blot analysis of extracts from HeLa cells, HUVEC cells, COLO cells and MCF-7 cells, using DNAJB11 antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human heart tissue using DNAJB11 antibody. Western blot analysis of extracts from HeLa cells, HUVEC cells, COLO cells and MCF-7 cells, using DNAJB11 antibody.)
References
Ohtsuka K., Cell Stress Chaperones 5:98-112(2000). Yu M., J. Biol. Chem. 275:24984-24992(2000). Bies C., Biol. Chem. 385:389-395(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,514 Da
NCBI Official Full Name
dnaJ homolog subfamily B member 11
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member B11
NCBI Official Symbol
DNAJB11
NCBI Official Synonym Symbols
DJ9; EDJ; Dj-9; ERj3; ABBP2; ERdj3; ERj3p; ABBP-2; UNQ537; PRO1080
NCBI Protein Information
dnaJ homolog subfamily B member 11
UniProt Protein Name
DnaJ homolog subfamily B member 11
Protein Family
UniProt Gene Name
DNAJB11
UniProt Synonym Gene Names
EDJ; ERJ3; HDJ9; ABBP-2; ER-resident protein ERdj3; ERdj3; ERj3p; hDj-9

NCBI Description

This gene encodes a soluble glycoprotein of the endoplasmic reticulum (ER) lumen that functions as a co-chaperone of binding immunoglobulin protein, a 70 kilodalton heat shock protein chaperone required for the proper folding and assembly of proteins in the ER. The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity. [provided by RefSeq, Mar 2014]

Uniprot Description

Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.

Research Articles on DNAJB11

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Product Notes

The DNAJB11 dnajb11 (Catalog #AAA852737) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The DNAJB11 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DNAJB11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000. Researchers should empirically determine the suitability of the DNAJB11 dnajb11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNAJB11, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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