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Western Blot (WB) (Western blot analysis of extracts from HepG2 cells, HeLa cells and 293 cells, using CMKLR1 antibody.)

CMKLR1 Antibody | anti-CMKLR1 antibody

CMKLR1 Antibody

Gene Names
CMKLR1; DEZ; RVER1; ChemR23; CHEMERINR
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Immunogen affinity purified
Synonyms
CMKLR1; CMKLR1 Antibody; Chemokine receptor-like 1; G-protein coupled receptor DEZ; G-protein coupled receptor ChemR23; CHEMR23; DEZ; CML1; anti-CMKLR1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
CMKLR1 Antibody detects endogenous levels of total CMKLR1
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
373
Applicable Applications for anti-CMKLR1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthesized peptide
Preparation and Storage
Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts from HepG2 cells, HeLa cells and 293 cells, using CMKLR1 antibody.)

Western Blot (WB) (Western blot analysis of extracts from HepG2 cells, HeLa cells and 293 cells, using CMKLR1 antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42 KD
NCBI Official Full Name
chemokine-like receptor 1 isoform a
NCBI Official Synonym Full Names
chemerin chemokine-like receptor 1
NCBI Official Symbol
CMKLR1
NCBI Official Synonym Symbols
DEZ; RVER1; ChemR23; CHEMERINR
NCBI Protein Information
chemokine-like receptor 1
UniProt Protein Name
Chemokine-like receptor 1
UniProt Gene Name
CMKLR1
UniProt Synonym Gene Names
CHEMR23; DEZ

Uniprot Description

Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).

Research Articles on CMKLR1

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Product Notes

The CMKLR1 cmklr1 (Catalog #AAA8514280) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CMKLR1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CMKLR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the CMKLR1 cmklr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CMKLR1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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