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Western Blot (WB) (Western blot analysis of extracts of HT-29 cellline, using CLDN3 antibody. |Immunohistochemistry of paraffin-embeddedhuman cervical cancer tissue using CLDN3antibody.)

CLDN3 Antibody | anti-CLDN3 antibody

CLDN3 Antibody

Gene Names
CLDN3; RVP1; HRVP1; C7orf1; CPE-R2; CPETR2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen affinity purified
Synonyms
CLDN3; CLDN3 Antibody; RVP1; HRVP1; C7orf1; CPE-R2; CPETR2; anti-CLDN3 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
CLDN3 Antibody detects endogenous levels of total CLDN3
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
220
Applicable Applications for anti-CLDN3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:100
Immunogen
A synthetic peptide of human CLDN3
Preparation and Storage
Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts of HT-29 cellline, using CLDN3 antibody. |Immunohistochemistry of paraffin-embeddedhuman cervical cancer tissue using CLDN3antibody.)

Western Blot (WB) (Western blot analysis of extracts of HT-29 cellline, using CLDN3 antibody. |Immunohistochemistry of paraffin-embeddedhuman cervical cancer tissue using CLDN3antibody.)
Related Product Information for anti-CLDN3 antibody
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23kDa
NCBI Official Full Name
claudin-3
NCBI Official Synonym Full Names
claudin 3
NCBI Official Symbol
CLDN3
NCBI Official Synonym Symbols
RVP1; HRVP1; C7orf1; CPE-R2; CPETR2
NCBI Protein Information
claudin-3
UniProt Protein Name
Claudin-3
Protein Family
UniProt Gene Name
CLDN3
UniProt Synonym Gene Names
C7orf1; CPETR2; CPE-R 2; CPE-receptor 2; hRVP1

NCBI Description

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Research Articles on CLDN3

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Product Notes

The CLDN3 cldn3 (Catalog #AAA8516557) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CLDN3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CLDN3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:100. Researchers should empirically determine the suitability of the CLDN3 cldn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLDN3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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