Testing Data
(Peptide-+)
ATRIP Antibody | anti-ATRIP antibody
ATRIP (Ab-68/72) Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
ATRIP; ATRIP (Ab-68/72) Antibody; ATIP; ATM and Rad3 related interacting protein; ATR-interacting protein; TREX1; anti-ATRIP antibody
Reactivity
Human, Mouse, Rat
Specificity
ATRIP (Ab-68/72) antibody detects endogenous levels of total ATRIP protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
664
Applicable Applications for anti-ATRIP antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human ATRIP around the phosphorylation site of serine 68/serine72 (L-A-SP-Q-A).
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
(Peptide-+)
Testing Data
(Peptide-+)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using ATRIP (Ab-68/72) antibody. Western blot analysis of extracts from NIH/3T3 cells, using ATRIP (Ab-68/72) antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using ATRIP (Ab-68/72) antibody. Western blot analysis of extracts from NIH/3T3 cells, using ATRIP (Ab-68/72) antibody.)
Immunofluorescence (IF)
(Peptide-+ Immunofluorescence analysis of HeLa cells, using ATRIP (Ab-68/72) antibody.)
Immunofluorescence (IF)
(Peptide-+ Immunofluorescence analysis of HeLa cells, using ATRIP (Ab-68/72) antibody.)
References
Heather L. Ball, Mol. Cell. Biol., May 2007; 27: 3367-3377. Jeremy S. Myers, Cancer Res., Jul 2007; 67: 6685-6690. Heather L. Ball, Mol. Biol. Cell, May 2005; 16: 2372-2381. Monica Venere, Cancer Res., Jul 2007; 67: 6100-6105.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
72,362 Da
NCBI Official Full Name
ATR-interacting protein isoform 3
NCBI Official Synonym Full Names
ATR interacting protein
NCBI Official Symbol
ATRIP
NCBI Protein Information
ATR-interacting protein
UniProt Protein Name
ATR-interacting protein
Protein Family
UniProt Gene Name
ATRIP
UniProt Synonym Gene Names
AGS1
NCBI Description
This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
Uniprot Description
Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Research Articles on ATRIP
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Product Notes
The ATRIP atrip (Catalog #AAA8509599) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The ATRIP (Ab-68/72) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ATRIP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000. Researchers should empirically determine the suitability of the ATRIP atrip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATRIP, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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