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Testing Data #2 (Western blot analysis of extracts from HepG2 cells, Jurkat cells and COS cells, using ATP1A2 antibody.)

ATP1A2 Antibody | anti-ATP1A2 antibody

ATP1A2 Antibody

Gene Names
ATP1A2; FHM2; MHP2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
ATP1A2; ATP1A2 Antibody; AT1A2; ATPase; Na+/K+ transporting; alpha 2 (+) polypeptide; EC 3.6.3.9; FHM2; MHP2; migraine; hemiplegic 2; Na+/K+-ATPase alpha 2; sodium pump 2; sodium-potassium ATPase; sodium/potassium-transporting ATPase alpha-2; sodium/potassium-transporting ATPase alpha-2 chain; anti-ATP1A2 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
ATP1A2 antibody detects endogenous levels of total ATP1A2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1020
Applicable Applications for anti-ATP1A2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human ATP1A2.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data #2

(Western blot analysis of extracts from HepG2 cells, Jurkat cells and COS cells, using ATP1A2 antibody.)

Testing Data #2 (Western blot analysis of extracts from HepG2 cells, Jurkat cells and COS cells, using ATP1A2 antibody.)
References
Shull M.M., J. Biol. Chem. 264:17532-17543(1989). Nagase T., DNA Res. 5:277-286(1998). Gregory S.G., Nature 441:315-321(2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
477
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
112,265 Da
NCBI Official Full Name
sodium/potassium-transporting ATPase subunit alpha-2
NCBI Official Synonym Full Names
ATPase Na+/K+ transporting subunit alpha 2
NCBI Official Symbol
ATP1A2
NCBI Official Synonym Symbols
FHM2; MHP2
NCBI Protein Information
sodium/potassium-transporting ATPase subunit alpha-2
UniProt Protein Name
Sodium/potassium-transporting ATPase subunit alpha-2
UniProt Gene Name
ATP1A2
UniProt Synonym Gene Names
KIAA0778; Na(+)/K(+) ATPase alpha-2 subunit

NCBI Description

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008]

Uniprot Description

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients.

Research Articles on ATP1A2

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Product Notes

The ATP1A2 atp1a2 (Catalog #AAA853656) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The ATP1A2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ATP1A2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:1000 ELISA: 1:1000. Researchers should empirically determine the suitability of the ATP1A2 atp1a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATP1A2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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