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Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue using AMPD1 antibody.)

AMPD1 Antibody | anti-AMPD1 antibody

AMPD1 Antibody

Gene Names
AMPD1; MAD; MADA; MMDD
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
AMPD1; AMPD1 Antibody; AMP deaminase 1; EC 3.5.4.6; Myoadenylate deaminase; AMP deaminase isoform M; anti-AMPD1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
AMPD1 antibody detects endogenous levels of total AMPD1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
780
Applicable Applications for anti-AMPD1 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human AMPD1.
Preparation and Storage
Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue using AMPD1 antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue using AMPD1 antibody.)
References
Gregory S.G., Nature 441:315-321(2006). Morisaki H., Hum. Mutat. 16:467-472(2000). Sjoeblom T., Science 314:268-274(2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
270
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
89,763 Da
NCBI Official Full Name
AMP deaminase 1 isoform 1
NCBI Official Synonym Full Names
adenosine monophosphate deaminase 1
NCBI Official Symbol
AMPD1
NCBI Official Synonym Symbols
MAD; MADA; MMDD
NCBI Protein Information
AMP deaminase 1
UniProt Protein Name
AMP deaminase 1
Protein Family
UniProt Gene Name
AMPD1

NCBI Description

Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]

Uniprot Description

AMP deaminase plays a critical role in energy metabolism.CautionIt is uncertain whether Met-1 or Met-34 is the initiator.

Research Articles on AMPD1

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Product Notes

The AMPD1 ampd1 (Catalog #AAA856552) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The AMPD1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AMPD1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:40000. Researchers should empirically determine the suitability of the AMPD1 ampd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AMPD1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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