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Western Blot (WB) (Western blot analysis of extracts from HepG2 cells and mouse muscle cells, using ADCK3 antibody.)

ADCK3 Antibody | anti-ADCK3 antibody

ADCK3 Antibody

Gene Names
COQ8A; COQ8; ADCK3; ARCA2; CABC1; SCAR9; COQ10D4
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
ADCK3; ADCK3 Antibody; Chaperone activity of bc1 complex-like; mitochondrial [Precursor]; Chaperone-ABC1-like; aarF domain-containing protein kinase 3; CABC1; PP265; anti-ADCK3 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
ADCK3 antibody detects endogenous levels of total ADCK3 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
647
Applicable Applications for anti-ADCK3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human ADCK3.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from HepG2 cells and mouse muscle cells, using ADCK3 antibody.)

Western Blot (WB) (Western blot analysis of extracts from HepG2 cells and mouse muscle cells, using ADCK3 antibody.)
References
Iiizumi M., Cancer Res. 62:1246-1250(2002). Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004). Gregory S.G., Nature 441:315-321(2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,537 Da
NCBI Official Full Name
atypical kinase COQ8A, mitochondrial
NCBI Official Synonym Full Names
coenzyme Q8A
NCBI Official Symbol
COQ8A
NCBI Official Synonym Symbols
COQ8; ADCK3; ARCA2; CABC1; SCAR9; COQ10D4
NCBI Protein Information
atypical kinase COQ8A, mitochondrial
UniProt Protein Name
Atypical kinase COQ8A, mitochondrial
UniProt Gene Name
COQ8A
UniProt Synonym Gene Names
Chaperone-ABC1-like

NCBI Description

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144, PubMed:21296186, PubMed:25540914, PubMed:27499294). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:25498144, PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (PubMed:25498144, PubMed:27499294). Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144).

Research Articles on ADCK3

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Product Notes

The ADCK3 coq8a (Catalog #AAA852803) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The ADCK3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ADCK3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the ADCK3 coq8a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADCK3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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